The 2025 Regional Joint Programme Report for Asia and the Pacific highlights substantial progress in expanding HIV prevention, strengthening community‑led responses, advancing gender equality, and ensuring sustainability amid funding constraints. Across the region, the Joint Programme supported governments, civil society and communities to scale up people‑centred, rights‑based HIV services. Major achievements include accelerated roll out of pre-exposure prophylaxis (PrEP), including preparation for long-acting options, strengthened harm reduction systems, expanded gender‑responsive services, and significant advances in sustainability, domestic financing and service continuity in emergency settings.
Asia and Pacific
The Joint Programme enabled major advances in combination HIV prevention including preparation for long-acting PrEP such as lenacapavir, long-acting cabotegravir and the dapivirine vaginal ring, while regional advocacy platforms strengthened momentum for equitable access. Harm reduction services expanded through updated methadone guidance and community led models, while treatment optimization was strengthened through an HIV drug resistance survey. Digital transformation expanded virtual HIV, hepatitis and STI services, including social media outreach, tele counselling, digital referrals and HIV self-testing, with hybrid models in at least three countries. The Maldives was validated as the first country to achieve the triple elimination of vertical transmission of HIV, syphilis and hepatitis B, a groundbreaking achievement made through integrated antenatal care, immunization and testing. Additionally, the Joint Programme spearheaded the launch of the Asia-Pacific Triple Elimination Roadmap, receiving progress data from 21 countries to guide implementation.
HIV-related community-led and rights-based actions were strengthened across the region. Efforts were made to reduce HIV related legal, administrative and social barriers which led to expansion of access to HIV, health and social services. Gender responsive HIV outcomes advanced through integration into comprehensive sexuality education (CSE) initiatives and there was prioritized support for CSE, teacher training and youth leadership, reaching millions of learners and enabling safer school environments.
The Joint Programme provided political, technical and financial support to countries to protect essential services and strengthen sustainability. This included the safeguarding of grants to support continuity of HIV services and the mobilization of domestic resources in at least three countries with rising epidemics. Over 50 600 people were registered in social protection schemes in one country while the Government committed to fully domestically finance HIV treatment. In another country, the National Assembly approved a new Disease Prevention Fund and an investment policy for the National Target Programme on Health Care, Population and Development (2026–2035), both expecting to boost domestic resources accessible to the HIV response. Midterm review of the Integrated Regional Action Plan for Hepatitis, HIV and STIs generated consolidated evidence on regional progress - showing strong declines in HIV mortality alongside persistent gaps in hepatitis diagnosis, STI surveillance and service integration for key populations. Regional political commitment on HIV and substance use was strengthened through a joint session at the seventy sixth WHO Regional Committee for the Western Pacific, engaging 38 countries and areas and catalysing shared priorities and coordinated responses. Furthermore, regional consultations for the Global AIDS Strategy (2026–2031) aligned 23 countries around prevention scale up, service integration and institutionalized community leadership.

